Dedicated to Improving the Lives of
Children, Adults & Families Affected by SYNGAP1

We are Bridging the Gap to Better Treatments and a Cure for SYNGAP1 Patients and Families

SYNGAP1 - Patient & Caregiver Voices
Externally Led -
Patient Focused Drug Development Meeting
Click on the Action Alert Button to learn more & register for the
Virtual SYNGAP1 - Patient & Caregiver Voices Meeting
scheduled for November 19, 2020
2020  International SYNGAP1 Scientific Conference
Click on the button above to learn more and register!
3rd International SYNGAP1 Virtual Scientific Conference &
Young Investigator Career Development Workshop

November 17 - 19, 2020
Questions?  We would love to hear from you!
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Making a Difference

What is Bridge the Gap?

Bridge the Gap – SYNGAP Education and Research Foundation (BTG) is the leading, 501(c)3 non-profit, patient advocacy organization dedicated to improving the quality of life for patients and families affected by SYNGAP1.

Our priorities include raising public awareness, patient and family advocacy initiatives, educational programs, scientific research conferences and financial support for research.

In addition, Bridge the Gap maintains the largest SYNGAP1 (MRD5) Online Natural History Data Registry in coordination with NORD and with grant funding provided by the FDA. The registry helps us provide the data needed to accelerate SYNGAP1 research.

We have also formed strategic partnerships and collaborations with a diverse group of SYNGAP1 stakeholders to help accelerate the pace of research and maximize our impact.


SYNGAP1 is a rare genetic disorder.

It can cause intellectual disability, epilepsy, autism, sensory
processing disorders and behavior challenges, ranging from mild to severe.

We are here for you

Patients, Families and Caregivers

Advocacy, Education, Research &
Clinical Centers of Excellence

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Syngap1 - awareness, advocacy & accelerated research

Action = Impact

We are Committed to a Better Future for All SYNGAP1 Patients and Families!

Watch our Video and Learn More About - BTG's SYNGAP1 STORY

Narrated by

Monica Weldon, Founder/CEO
Bridge the Gap - SYNGAP Education and Research Foundation

Monica Weldon, President/CEO
Bridge the Gap - SYNGAP ERF

Learn About
Our History &
Meet Our Team

In September 2014, Monica Weldon, along with a small group of families, each with a child diagnosed with a SYNGAP1 mutation, came together to form Bridge the Gap – SYNGAP Education and Research Foundation.  

United by their common bond, it drove their desire to raise awareness and search out treatments to improve the quality of life for their children.

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Leading the Charge in Syngap1 Research

Our Innovative Collaborations with Reseachers and
Clinicians are Making an Impact!

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